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Nomazol CAS NO.: 8131044716
Hereditary Angioedema: for prophylacc use to decrease frequency and severity of aacks of angioedema.
 
Details

NOMAZOL 10

Stanozolol

COMPOSITION:

Each film-coated tablet contains:

Stanozolol USP 10mg

Colour: Approved colour used in coang

INDICATIONS AND USAGE:

Hereditary Angioedema: for prophylacc use to decrease frequency and severity of aacks of angioedema. Muscle Anabolism: for adjuncve therapy in paents for weight gain following severe muscular atrophy associated with extensive surgery, chronic infecons, long term hospitalizaon, or sever trauma. Corcosteroid atrophy: to reduce muscle wasng during prolonged corcosteroid use.

CONTRA-INDICATIONS:

1. Female paents due to risk of virilizaon and fatal harm. 2. Male paents with known or suspected carcinoma of the breast, prostate, or tess. 3. Paents with hypercalcaemia as anabolic steroids may smulate osteolyc bone resorpon. 4. Paents with cardiovascular disorders, renal or hepac impairment, epilepsy, migraines, or diabetes mellitus. 5. Nephrosis or the nephroc phase of nephris. 6. Hypersensivity to stanozolol.

DRUG INTERACTIONS:

Nomazol 10 may increase sensivity to ancoagulants; therefore, dosage of an ancoagulant may have to be decreased in order to maintain the prothrombin me at the desired therapeuc level.

PRECAUTIONS:

General: Women should be observed for signs of virilisaon (deepening of the voice, hirsusm, acne, and clitoromegaly). To prevent irreversible change, drug therapy must be disconnued, or the dosage significantly reduced. Such virilisaon is usual following androgenic anabolic steroid use at high doses. Some virilising changes in women are irreversible even aer prompt disconnuance of therapy and are not prevented by concomitant use of estrogens. Menstrual irregularies may also occur. The insulin or oral hypoglycemic dosage may need adjustment in diabec paents who receive anabolic steroids. Informaon for the Paent. The physician should instruct paents to report any of the following side effects of androgens:

Adult or Adolescent Males: Too frequent or persistent erecons of the penis, appearance or aggravaon of acne. Women: Hoarseness, acne, changes in menstrual periods, or more hair on the face. All Paents: Any nausea, voming, changes in skin color, or ankle swelling. Laboratory Tests: Women with disseminated breast carcinoma should have frequent determinaon of urine and serum calcium levels. Because of the hepatotoxicity associated with the use of 17-alpha-alkylated androgens, liver funcon tests should be obtained periodically.

Periodic (every 6 months) x-ray examinaons of bone age should be made during treatment of prepubertal paents to determine the rate of bone maturaon and the effects of androgenic anabolic steroid therapy on the epiphy seal centres. In common with other anabolic steroids. Stanobol 10 has been reported to lower the level of high-density lipoproteins and raise the level of low density lipoproteins. These changes usually revert to normal on disconnuaon of treatment. Increased low-density lipoproteins and decreased high-density lipoproteins are considered cardiovascular risk factors.

DOSAGE AND ADMINSTRATION:

Muscle anabolism: 10-30 mg taken orally each day in divided doses for duraon of 4-6 weeks. Hereditary angioedema: The dosage requirement for connuous treatment of hereditary angioedema with Nomazol 10. Should be individualized on the basis of the clinical response of the paent. Commonly 2-6 mg taken orally each day in divided doses inially and reduced by physician thereaer. Effecve dose for male: 50-100 mg per day Effcve dose for female: 2.5-10 mg per day

PRESENTATIONS:

4 blister strips of 25 tablets are packed in a printed carton along with a leaflet. OR 100 Tablets in Plasc Bole

STORAGE DIRECTIONS:

Store at room temperature below 25C. and away from excess heat & moisture. Keep out of reach of children! Do not freeze.

 
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